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Lescol Consumer Information

LESCOL

Generic Name: fluvastatin (FLEW va stah tin)

Brand Names: Lescol, Lescol XL

What is the most important information I should know about fluvastatin?

• Do not take fluvastatin without first talking to your doctor if you have liver disease.
• Alcohol and fluvastatin can both damage your liver. Discuss with your doctor the amount of alcohol that you drink so that it can be determined if fluvastatin is the best choice for lowering your cholesterol.
• Do not take fluvastatin if you are pregnant, if you are planning a pregnancy, or if you are breast-feeding a baby.
• Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if it is accompanied by a fever, flulike symptoms, or yellowing of your skin or eyes.

What is fluvastatin?

• Fluvastatin blocks the production of cholesterol (a type of fat) in the body.
• Fluvastatin is used to reduce the amounts of LDL (bad) cholesterol and total cholesterol in your blood. Fluvastatin also reduces the amounts of triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
• Fluvastatin may also be used for purposes other than those listed in this medication guide.

Who should not take fluvastatin?

• Do not take fluvastatin without first talking to your doctor if you have liver disease.
• Before taking fluvastatin, tell your doctor if you
• have kidney disease,
• drink alcoholic beverages,
• have a chronic muscular disease, or
• have a blood disorder.
• You may not be able to take fluvastatin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Fluvastatin is in the FDA pregnancy category X. This means that fluvastatin will cause birth defects if it is taken during pregnancy. Cholesterol is very important for the proper development of a baby. Do not take fluvastatin if you are pregnant or if you are planning a pregnancy.
• Fluvastatin passes into breast milk and may harm a nursing infant. Do not take fluvastatin without first talking to your doctor if you are breast-feeding a baby.
• Fluvastatin has not been approved for use by children younger than 18 years of age.

How should I take fluvastatin?

• Take fluvastatin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• For the greatest effect, fluvastatin is usually taken at bedtime or with an evening meal. Fluvastatin may also be taken twice daily. Follow your doctor's directions.
• Do not crush, chew, or break the extended-release tablets (Lescol XL). Swallow them whole.
• Your doctor will probably want to monitor your liver function with blood tests before starting treatment with fluvastatin and at twelve weeks after both the start of your treatment and any increase in dose. Depending on the results of these tests, your doctor can determine how much monitoring you will require.
• Eat a low-fat, low-cholesterol diet. To realize beneficial effects from fluvastatin, avoid fatty, high-cholesterol foods.
• Do not stop taking fluvastatin without first talking to your doctor. It may be weeks or months before beneficial effects are seen from fluvastatin.
• Store fluvastatin at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

• Seek emergency medical attention.
• Symptoms of a fluvastatin overdose include nausea, diarrhea, stomach distress, and indigestion.

What should I avoid while taking fluvastatin?

• Alcohol and fluvastatin can both damage your liver. Discuss with your doctor the amount of alcohol that you drink so that it can be determined if fluvastatin is the best choice for lowering your cholesterol.

What are the possible side effects of fluvastatin?

• If you experience any of the following serious side effects, stop taking fluvastatin and call your doctor immediately:
• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
• muscle aches, pain, or weakness;
• "flu-like" symptoms;
• decreased urine or rust-colored urine;
• blurred vision; or
• yellowing of your eyes or skin.
• Other, less serious side effects may be more likely to occur. Continue to take fluvastatin and talk to your doctor if you experience
• gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea;
• cough;
• headache; or
• insomnia.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect fluvastatin?

• Do not take fluvastatin without first talking to your doctor if you are taking any of the following medicines:
• cyclosporine (Sandimmune, Neoral);
• gemfibrozil (Lopid);
• niacin (Nicolar, Nicobid, Nicotinex, others); or
• clarithromycin (Biaxin);
• erythromycin (E-Mycin, E.E.S., Ery-Tab, Ilotycin, Eryc, PCE, Ilosone, others).
• These medications may interact with fluvastatin and damage your muscles.
• Before taking fluvastatin, tell your doctor if you are taking any of the following medicines:
• other cholesterol-lowering drugs such as cholestyramine (Questran) or colestipol (Colestid);
• digoxin (Lanoxin, Lanoxicaps); or
• warfarin (Coumadin).
• You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with fluvastatin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about fluvastatin written for health professionals that you may read.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Limitations of This Canadian Pharmacy Information

Efforts have been made to ensure that the information provided here is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information does not endorse drugs, diagnose patients or recommend therapy. This is an educational resource only intended to supplement but not to replace the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. This site does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

Full public license and copyright information is available separately from Cerner Multum, Inc.

Version: 7.02. Revision Date: 2/14/03.